PEFAT: Boosting Semi-Supervised Medical Image Classification via Pseudo-Loss Estimation and Feature Adversarial Training

Qingjie Zeng · Yutong Xie · Zilin Lu · Yong Xia

West Building Exhibit Halls ABC 316
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Wed 21 Jun 4:30 p.m. PDT — 6 p.m. PDT


Pseudo-labeling approaches have been proven beneficial for semi-supervised learning (SSL) schemes in computer vision and medical imaging. Most works are dedicated to finding samples with high-confidence pseudo-labels from the perspective of model predicted probability. Whereas this way may lead to the inclusion of incorrectly pseudo-labeled data if the threshold is not carefully adjusted. In addition, low-confidence probability samples are frequently disregarded and not employed to their full potential. In this paper, we propose a novel Pseudo-loss Estimation and Feature Adversarial Training semi-supervised framework, termed as PEFAT, to boost the performance of multi-class and multi-label medical image classification from the point of loss distribution modeling and adversarial training. Specifically, we develop a trustworthy data selection scheme to split a high-quality pseudo-labeled set, inspired by the dividable pseudo-loss assumption that clean data tend to show lower loss while noise data is the opposite. Instead of directly discarding these samples with low-quality pseudo-labels, we present a novel regularization approach to learn discriminate information from them via injecting adversarial noises at the feature-level to smooth the decision boundary. Experimental results on three medical and two natural image benchmarks validate that our PEFAT can achieve a promising performance and surpass other state-of-the-art methods. The code is available at

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